Publicaciones científicas (últimos 16 años) / Scientific publications (last 16 years)


Agostino, P. V., Lusk, N. A., Meck, W. H., Golombek, D. A., & Peryer, G. (2020). Daily and seasonal fluctuation in Tawny Owl vocalization timing. Plos one, 15(4), e0231591.

Tortello, C*., Agostino, P. V*., Folgueira, A., Barbarito, M., Cuiuli, J. M., Coll, M., Golombek, D. A., Plano, S. A. & Vigo, D. E. (2020). Subjective Time Estimation in Antarctica: the impact of circadian dysregulation and isolation on a time production task. Neuroscience Letters 134893. doi: 10.1016/j.neulet.2020.134893. *Igual contribución.

Goldin AP, Sigman M, Braier G, Golombek DA, Leone MJ. Interplay of chronotype and school timing predicts school performance. Nat Hum Behav. 2020 Feb 10. doi: 10.1038/s41562-020-0820-2.

Acosta J, Bussi IL, Esquivel M, Höcht C, Golombek DA, Agostino PV. Circadian modulation of motivation in mice. Behav Brain Res. 2020 Mar 16;382:112471. doi: 10.1016/j.bbr.2020.112471.

Bainbridge C, Clites BL, Caldart CS, Palacios B, Rollins K, Golombek DA, Pierce JT, Vidal-Gadea AG. Factors that influence magnetic orientation in Caenorhabditis elegans.J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2019 Aug 28. doi: 10.1007/s00359-019-01364-y.

Folgueira A, Simonelli G, Plano S, Tortello C, Cuiuli JM, Blanchard A, Patagua A, Brager AJ, Capaldi VF, Aubert AE, Barbarito M, Golombek DA, Vigo DE. Sleep, napping and alertness during an overwintering mission at Belgrano II Argentine Antarctic station. Sci Rep. 2019 Jul 26;9(1):10875. doi: 10.1038/s41598-019-46900-7.

Alessandro MS, Golombek DA, Chiesa JJ. Protein Kinases in the Photic Signaling of the Mammalian Circadian Clock. Yale J Biol Med. 2019 Jun 27;92(2):241-250. eCollection 2019 Jun. Review.

Chiesa JJ, Baidanoff FM, and Golombek DA (2018). Don’t just say no: Differential pathways and pharmacological responses to diverse nitric oxide donors. Biochem Pharmacol 156:1-9.

Laje, R., Agostino, P.V., and Golombek, D.A. (2018). The times of our lives: interaction among different biological periodicities. Frontiers in Integrative Neuroscience 12, 10.

Mul Fedele, M.L., Galiana, M.D., Golombek, D.A., Muñoz, E.M., and Plano, S.A. (2018). Alterations in Metabolism and Diurnal Rhythms following Bilateral Surgical Removal of the Superior Cervical Ganglia in Rats. Front Endocrinol (Lausanne) 8:370.
doi: 10.3389/fendo.2017.00370.

Leone MJ, Salles A, Pulver A, Golombek DA, and Sigman M. (2018). Time drawings: Spatial representation of temporal concepts. Conscious Cogn 59:10-25.

Vidal-Gadea, A,, Caldart, C., Bainbridge, C., Clites, B., Palacious, B., Bakhtiari, L., Gordon, V., Golombek, D.A., and Pierce, J. (2018). Temporal and spatial factors that influence magnetotaxis in C. elegans. bioRxiv, p:252700.

Gonzalez MMC, Golombek DA.. Editorial: Let There Be Light: Biological Impact of Light Exposure in the Laboratory and the Clinic. Front Neurol. 2018 Oct 9;9:851. doi: 10.3389/fneur.2018.00851. eCollection 2018.

Agostino, P.V., Acosta, J., and Meck, W.H. (2017). Neurobiology of Circadian and Interval. Timing. In: eLS. John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/9780470015902.a0027161.

Duhart, J.M., Brocardo, L., Caldart, C.S., Marpegan, L., Golombek, D.A. (2017). Circadian Alterations in a Murine Model of Hypothalamic Glioma. Front Physiol. 2017 Oct 30;8:864. doi: 10.3389/fphys.2017.00864. eCollection 2017.

Plano SA, Casiraghi LP, García Moro P, Paladino N, Golombek DA, Chiesa JJ. (2017). Circadian and Metabolic Effects of Light: Implications in Weight Homeostasis and Health. Front Neurol. 2017 Oct 19;8:558. doi: 10.3389/fneur.2017.00558. eCollection 2017. Review.

Acosta, J., Campolongo, M.A., Höcht, C., Depino, A.M., Golombek, D.A., and Agostino, P.V. (2017). Deficits in temporal processing in mice prenatally exposed to Valproic Acid.
Eur J Neurosci. 2017 Jun 14. doi: 10.1111/ejn.13621.

Agostino, P.V., Gatto, E.M., Cesarini, M., Etcheverry, J.L, Sanguinetti, A., and Golombek, D.A. (2017). Deficits in temporal processing correlate with clinical progression in Huntington’s disease. Acta Neurol Scand. 2017;00:1–8. doi:10.1111/ane.12728.

Goya, M. E., Romanowski, A., Caldart, C.S., Bénard, C.Y., and Golombek, D.A. (2016). Circadian rhythms identified in Caenorhabditis elegans by in vivo long-term monitoring of a bioluminescent reporter. doi: 10.1073/pnas.1605769113.

Agostino, P. V., and Cheng, R-K (2016). Contributions of Dopaminergic Signaling to Timing Accuracy and Precision. Curr Opin Behav Sci. 8, 153-160.

Casiraghi, L.P., Alzamendi, A., Giovambattista, A., Chiesa, J.J., Golombek, D.A. (2016). Effects of chronic forced circadian desynchronization on body weight and metabolism in male mice. Physiol Rep. 4(8). pii: e12743.

Bellone G.J., Plano S.A., Cardinali D.P., Pérez Chada D., Vigo D.E, Golombek D.A. (2016) Comparative analysis of actigraphy performance in healthy young subjects. Sleep Science. In press. doi:10.1016/j.slsci.2016.05.004

Duhart, J.M., Brocardo, L., Mul Fedele, M.L., Guglielmotti, A., Golombek, D.A. (2016). CCL2 mediates the circadian response to low dose endotoxin. Neuropharmacology 108:373-81.

Cardinali, D.P., Golombek, D.A., Rosenstein, R.E., Brusco, L.I., Vigo, D.E. (2016). Assessing the efficacy of melatonin to curtail benzodiazepine/Z drug abuse. Pharmacol Res. 109:12-23.

de la Iglesia HO, Moreno C, Lowden A, Louzada F, Marqueze E, Levandovski R, Pilz LK, Valeggia C, Fernandez-Duque E, Golombek DA, Czeisler CA, Skene DJ, Duffy JF, Roenneberg T. (2016). Ancestral sleep. Curr Biol. 26(7):R271-2.

Golombek D.A. (2016). Notes for a science of cannabis. Vertex, Nov;XXVII(130):430-433. Spanish.

Bussi, I. L., Levín, G., Golombek, D. A., Agostino, P. V. (2015). Melatonin modulates interval timing in rats: effect of pinealectomy. Int J Comp Psychol, vol 28.

Camargo-Sánchez A., Niño C.L., Sánchez L., Echeverri S., Gutiérrez D.P., Duque A.F., Pianetta, O., Jaramillo-Gomez J.A., Pilonieta M.A., Cataño N., Arboleda H., Agostino P.V., Álvarez-Baron C.P., Vargas R. (2015). Circadian Nursing Care for the Hospitalized Patient: a proposal for a middle-range theory. Open Nurs J 9: 1-9.

Herrero A, Romanowski A, Meelkop E, Schoofs A, Golombek DA. (2015). Pigment-dispersing factor (Pdf) signaling in the circadian system of Caenorhabditis elegans. Genes Brain Behav. 14(6):493-501.

Leone MJ, Beaule C, Marpegan L, Simon T, Herzog ED, Golombek DA. (2015). Glial and light-dependent glutamate metabolism in the suprachiasmatic nuclei. Chronobiol Int. 32(4):573-8.

Golombek DA, Pandi-Perumal SR, Brown GM, Cardinali DP. (2015). Some implications of melatonin use in chronopharmacology of insomnia. Eur J Pharmacol. 762:42-8.

de la Iglesia HO, Fernández-Duque E, Golombek DA, Lanza N, Duffy JF, Czeisler CA, Valeggia CR. (2015). Access to Electric Light Is Associated with Shorter Sleep Duration in a Traditionally Hunter-Gatherer Community. J Biol Rhythms 30(4):342-50.

Romanowski A, Garavaglia M, Goya E, Ghiringhelli PD, Golombek DA. (2014). Conservation of circadian clock proteins in the phylum Nematoda. PLoS ONE 9(11): e112871.

Högl B., Agostino P.V., Peralta M.C., Gershanik O., and Golombek D.A. (2014). Alterations in time estimation in multiple system atrophy. Basal Ganglia 4: 95-99.

Bussi I.L., Levín G., Golombek D.A., and Agostino P.V. (2014). Involvement of dopamine signaling in the circadian modulation of interval timing. Eur J Neurosci 40(1):2299-310, doi: 10.1111/ejn.12569.

Golombek D.A., Bussi I.L., and Agostino P.V. (2014). Minutes, days and years: molecular interactions among different scales of biological timing. Philos Trans R Soc Lond B Biol Sci. 369(1637):20120465.

Paladino N, Mul Fedele ML, Duhart JM, Marpegan L, Golombek DA. (2014). Modulation of mammalian circadian rhythms by tumor necrosis factor-α. Chronobiol Int 31: 668-679.

Baidanoff F, Plano SA, Doctorovich F, Suarez F, Golombek DA, Chiesa JJ. (2014). N-nitrosomelatonin enhances photic synchronization of mammalian circadian rhythms. J Neurochem 129(1):60-71.

Agostino P.V., Cheng R.K., Williams C.L., West A.E. and Meck W.H. (2013). Acquisition of Response Thresholds for Timed Performance is Regulated by a Calcium-Responsive Transcription Factor, CaRF. Genes, Brain & Behavior 12: 633–644.

Golombek D.A., Casiraghi L.P., Agostino P.V., Paladino N., Duhart J., Plano S.A. and Chiesa J.J. (2013). The times they are a-changing: effect of circadian desynchronization on physiology and disease. J. Physiol. Paris 107(4):310-22.

Paladino N, Duhart JM, Mul Fedele ML, Golombek DA. Characterization of locomotor activity circadian rhythms in athymic nude mice. J Circadian Rhythms. 2013 Feb 1;11(1):2.
Duhart JM, Marpegan L, Leone MJ, Golombek DA. (2013). Role of astrocytes in the immune-circadian signalling. Adv Neuroimmune Res 4: 85-96.

Duhart JM, Leone MJ, Paladino N, Evans JA, Castanon-Cervantes O, Davidson AJ; Golombek DA. (2013). SCN astrocytes modulate the circadian clock in response to TNF-a. J Immunol 191(9): 4656-64.

Cermakian N; Lange T; Golombek DA; Sarkar D; Nakao A; Shibata S; Mazzoccoli G. (2013). Cross-talk Between the Circadian Clock Circuitry and the Immune System. Chronobiol Int 30 (7):870-888.

Fernandez DC; Sande PH; de Zavalia N; Belforte N; Dorfman D; Casiraghi LP; Golombek DA; Rosenstein RE. (2013). Effect of experimental diabetic retinopathy on the non-image forming visual system. Chronobiol Int 30: 583-97.

Plano SA, Agostino PV, de la Iglesia HO, Golombek DA. cGMP-phosphodiesterase inhibition enhances photic responses and synchronization of the biological circadian clock in rodents. PLoS One. 2012;7(5):e37121.

Leone MJ, Marpegan L, Duhart JM, Golombek DA. Role of proinflammatory cytokines on lipopolysaccharide-induced phase shifts in locomotor activity circadian rhythm. Chronobiol Int. 2012 Jul;29(6):715-23.

Casiraghi LP, Oda GA, Chiesa JJ, Friesen WO, Golombek DA. Forced desynchronization of activity rhythms in a model of chronic jet lag in mice. J Biol Rhythms. 2012 Feb;27(1):59-69.

Migliori ML, Romanowski A, Simonetta SH, Valdez D, Guido M, Golombek DA. Daily variation in melatonin synthesis and arylalkylamine N-acetyltransferase activity in the nematode Caenorhabditis elegans. J Pineal Res. 2012 Aug;53(1):38-46.

Katz ME, Margulis F, Schiavelli R, Arias P, Head GA, Golombek DA. Disruption of Transitional Stages in 24-h Blood Pressure Recording in Renal Transplant Recipients. Front Neurol. 2012;3:35. doi: 10.3389/fneur.2012.00035.

Katz ME; Ríos F; Sagardía; Pezzola E; Sobrero P; Arias P; Yunk O; Maskin B; Golombek DA. Disruptions in 24-hour profile of hemodynamic parameters in severe sepsis and septic shock. Sleep Science 5: 52-60, 2012.

Lanzani MF; de Zavalia N; Fontana H; Keller Sarmiento MI; Golombek DA; Rosenstein RE. Circadian activity rhythm alterations in patients with advanced glaucoma. Chronobiol Int. 29: 911-919: 2012.

Videnovic A; Golombek DA. Circadian and Sleep Disorders in Parkinson’s Disease. Exper Neurol 243:45-56, 2012.

Migliori ML, Simonetta SH, Romanowski A, Golombek DA. Circadian rhythms in metabolic variables in Caenorhabditis elegans. Physiol Behav. 2011 Jun 1;103(3-4):315-20.

Agostino P.V., Golombek D.A., and Meck W.H. (2011). Unwinding the molecular basis of interval and circadian timing. Front. Integr. Neurosci. 5: 64. doi: 10.3389/fnint.2011.00064.

Agostino PV, do Nascimento M, Bussi IL, Eguía MC, Golombek DA. Circadian modulation of interval timing in mice. Brain Res. 2011 Jan 25;1370:154-63.

Romanowski A, Migliori ML, Valverde C, Golombek DA. Circadian variation in Pseudomonas fluorescens (CHA0)-mediated paralysis of Caenorhabditis elegans. Microb Pathog. 2011 Jan;50(1):23-30.

de Zavalía N, Plano SA, Fernandez DC, Lanzani MF, Salido E, Belforte N, Keller Sarmiento MI, Golombek DA, Rosenstein RE. Effect of experimental glaucoma on the non-image forming visual system. J Neurochem 117(5): 904-914, 2011.

Golombek DA, Rosenstein RE. Physiology of circadian entrainment. Physiol Rev. 2010 Jul;90(3):1063-102. doi: 10.1152/physrev.00009.2009.

Golombek DA. Educating the brain. Am J Psychol, 374-376, 2010.

Paladino N, Leone MJ, Plano SA, Golombek DA. Paying the circadian toll: the circadian response to LPS injection is dependent on the Toll-like receptor 4. J Neuroimmunol. 2010 Aug 25;225(1-2):62-7.

Casiraghi LP, Croci DO, Poirier F, Rabinovich GA, Golombek DA. “Time sweet time»: circadian characterization of galectin-1 null mice. J Circadian Rhythms. 2010 Apr 19;8:4.

Plano SA, Golombek DA, Chiesa JJ. Circadian entrainment to light-dark cycles involves extracellular nitric oxide communication within the suprachiasmatic nuclei. Eur J Neurosci. 2010 Mar;31(5):876-82.

Casiraghi L; Martino D; Marengo E; Igoa A; Ais E; Strejilevich S; Golombek D. Human period-3 gene is involved in diurnal preference in an Argentinean population of bipolar disorders patients. Sleep Science, 3(1):22-27.

Romanowski A; Migliori ML; Valverde C: Golombek D. Circadian variation in Pseudomonas fluorescens (CHA0)-mediated paralysis of Caenorhabditis elegans. Microb Pathogen, 50: 23-30, 2010.

De Zavalía N; Golombek DA, Silberman M; Rosenstein RE. Circadian variations of Prostaglandin E2 and F2α release in the Golden Hamster retina. J Neurochem, 112: 972-979, 2010.

Agostino PV, Harrington ME, Ralph MR, Golombek DA. Casein kinase I-epsilon and circadian photic entrainment in hamsters. Chronobiol Int 26(1): 1-8, 2009.

Cardinali DP; Golombek DA. Let there be sleep – on time. Lancet 373: 439-440, 2009.
Marpegan L; Leone MJ; Katz ME; Sobrero PM; Golombek DA. Diurnal rhythm in endotoxin-induced mortality in mice: correlation with proinflammatory factors and lack of circadian variation. Chronobiology International 26(7):1430-1442, 2009.

Simonetta SH; Migliori ML; Romanowski A; Golombek DA. Timing of locomotor activity circadian rhythms in Caenorhabditis elegans. PLoS ONE 4(10):e7571. 2009.

Bekinschtein T; Cologan V; Dahmen B; Golombek DA. You are only coming through in waves: wakefulness variability and assessment in patients with impaired consciousness. Progress en Brain Research 177: 171-189, 2009.

Bekinschtein T; Golombek DA; Coleman V; Manes F. Circadian rhythms in the vegetative state. Brain Injury 23(11):915–919, 2009.

Agostino PV, Plano SA, Golombek DA. Circadian and pharmacological regulation of casein kinase I in the hamster SCN. J Genetics 87(5): 467-471, 2008.

Pizzio GA, Golombek DA. Photic regulation of MAP kinase phosphatases MKP1/2 and MKP3 in the hamster suprachiasmatic nuclei. J Molec Neurosci, 34(2):187-92, 2008.

Katz ME, Simonetta SH, Ralph MR, Golombek DA. Immunosuppressant calcineurin inhibitors phase shift circadian rhythms and inhibit circadian responses to light. Pharmacol Biochem Behav 90: 763-768, 2008.

Simonetta SH, Romanowski A, Minitti AN, Inestrosa NC, Golombek DA. Circadian stress resistance in C. elegans. J Comp Physiol A 194 (9): 821-828, 2008.

Cardinali DP; Golombek, DA. Mind, Brain, Education, and Biological Timing. Mind, Brain, and Education 2(1): 1-6, 2008.

Perez-Lloret S; Risk M; Golombek DA; Cardinali DP; Sanchez R; Ramirez A. Blunting of circadian rhythms and increased acrophase variability in asleep hypertensive subjects. Chronobiol Int 25(1): 99-113, 2008.

Agostino PA; Plano SA; Golombek DA. Sildenafil accelerates reentrainment of circadian rhythms. Proc Nat Aca Sci (USA), 104(23): 9834-9839, 2007.

Plano SA, Agostino PV, Golombek DG. Extracellular nitric oxide signalling in the mammalian circadian system. FEBS Letters 581: 5500–5504, 2007.

Simonetta, SH; Golombek DA. An automated tracking system for C. elegans locomotor behavior and circadian studies application. J Neurosci Methods, 161(3): 273-280, 2007.

Yannielli PC; Molyneux P; Harrington ME; Golombek DA. Ghrelin effects on the circadian system of mice. J Neurosci 27(11): 2890-2895, 2007.

Leone MJ, Marpegan L; Chiesa JJ; Golombek DA. A time to kill and a time to heal. Pathophysiological interactions between the circadian and the immune systems. Physiological Minireviews 2 (10): 60-69, 2007.

Leone MJ, Marpegan L, Bekinschtein T, Costas MC, Golombek DA. Suprachiasmatic astrocytes as an interphase for immune-circadian signalling. J Neurosci Res, 84: 1521-1527, 2006.

Hainich EC; Pizzio GA; Golombek DA. Constitutive activation of the ERK-MAPK pathway in the suprachiasmatic nuclei inhibits circadian resetting. FEBS Letters, 580: 6665-668, 2006.

Marpegan, L.; Bekinschtein, T.; Costas, M.R.; Golombek, D.A. Effects of LPS on the circadian system. J Neuroimmunol, 160(1-2):102-9, 2005.

Pizzio GA, Hainich EC, Plano, SA, Ralph MR, Golombek DA. Nerve growth factor-induced circadian phase shifts and MAP kinase activation in the hamster SCN. Eur J Neurosci 22(3): 665-671, 2005.

Agostino, P., Ferreyra, G.; Murad, A.; Watanabe, Y; Golombek, D. Diurnal, circadian and photic regulation of calcium/calmodulin-dependent kinase II and neuronal nitric oxide synthase in the hamster suprachiasmatic nuclei. Neurochem Int 44(8):617-25, 2004.

Golombek, D.A., Agostino, P.V., Plano, S.A., Ferreyra, G.A. Signaling in the mammalian circadian clock: the NO/cGMP pathway. Neurochem Int. 45(6):929-36, 2004.

Cheng, H.Y., Obrietan, K., Cain, S.W., Lee, B.Y., Agostino, P.V., Joza, N.A., Harrington, M.E., Ralph, M.R., Penninger, J.M. Dexras1 potentiates photic and suppresses nonphotic responses of the circadian clock. Neuron 43(5):715-28, 2004.

Marpegan, L.; Freudenthal, R.; Ferreyra, G.; Romano, A.; Golombek, D. Participation of transcription factors from the Rel/A-NFkB family in the circadian system. Neurosci Lett, 358(1):9-12, 2004.

Bekinschtein, T.A.; Negro, A.; Goldín, A.; Fernández, M.P.; Rosenbaum, S. and Golombek, D.A. Seasonality in a Mapuche native population. Biol Rhythms Res 35 (1-2): 145-152, 2004.

Simonetta, S.; Golombek, D. Procedimiento y dispositivo de registro locomotor de organismos pequeños y registro comportamental obtenido. Autores: CONICET – Universidad Nacional de Quilmes. Presentado en junio de 2006.