English version

Precise timing is ubiquitous and of great importance for physiology and behavior. Indeed, biological timing includes diverse time-related mechanisms that encompass several orders of magnitude, from microsecond processing to seasonal rhythms.
In the Laboratory of Chronobiology we study biological timing, with special emphasis on two temporal scales: circadian timing and time estimation in the seconds-to-minutes range.
Circadian timing refers to the range of the 24-h, and governs a large array of physiological, metabolic and behavioral functions. In mammals, the circadian clock is located in the suprachiasmatic nuclei (SCN) of the hypothalamus. Most – if not all – organisms exhibit daily and circadian rhythms with periods of ca. 24-h, which also serve as the basis for seasonal-encoding mechanisms and might be related to lifespan-related processes. In the seconds-to-minutes range, interval timing is involved in a number of fundamental behaviors such as foraging, decision-making and learning, via activation of cortico-striatal circuits.

Research lines

  • Signaling pathways involved in photic synchronization of the mammalian circadian clock.
  • Interactions between the circadian system and the immune system.
  • Role of glia in the intercellular communication.
  • Analysis of behavioral and metabolic variables through the development of animal models with circadian disorders.
  • Assessment of risk factors and sleep – wake cycle in different populations at risk.
  • Temporal processing in the seconds-to-minutes range: interaction with the circadian system.
  • Daily variations in decision making.
  • Circadian rhythms in Caenorhabditis elegans.

Staff

DIRECTOR
Dr. Diego A. Golombek
Full Professor
National University of Quilmes/CONICET

RESEARCHES
Dr. Juan J. Chiesa
Associate Professor
National University of Quilmes/CONICET

Dr. Patricia V. Agostino
Associate Professor
National University of Quilmes/CONICET

Dr. Luciano Marpegan
Assistant Professor
National University of Quilmes/CONICET

Dr. Natalia Paladino
Assistant Professor
National University of Quilmes/CONICET

Dr. Santiago A. Plano
Assistant Professor
National University of Quilmes/CONICET

Dr. María Juliana Leone
Assistant Professor
National University of Quilmes/CONICET

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POST-DOCS

Dr. M. Laura Migliori
National University of Quilmes

Dr. M. Rosana Rota
National University of Quilmes

Ph.D. STUDENTS

Lic. Fernando M. Baidanoff
M.Sc. in Biotechnology

Lic. Malena Mul Fedele
M.Sc. in Biotechnology

Lic. M. Soledad Alessandro
M.Sc. in Biotechnology

Ms. Eng. Carlos Caldart (Charly)
Engineer in Biophysics
Master in Medical Physics

Lic. Melisa Lambert
M.Sc. in Biotechnology

Lic. Julieta Acosta
M.Sc. in Biotechnology

Ms. Paula García Moro
Master in Sport Sciences

Lic. Lucia Rey Alvarez
M.Sc. in Biotechnology

Lic. Giannina Bellone
Ms. In Psychology

STUDENTS

Ignacio Aiello
Biotechnology

Laura Trebucq
Biotechnology

FORMER MEMBERS

Eugenia Goya (Euge)
Fernanda Román (Fer2)
Ivana Bussi (Ivy)
Leandro Casiraghi (Lea)
Luciano Brum (Lucho)
Agustín Carpaneto (Agus)
Lucila Brocardo (Lu)
José Duhart (Jose)
Jonathan Modernel (Jony)
Andrés Romanowski (Andrew)
Anastasia Herrero (Anas)
Micaela do Nascimento (Mica)
Gastón Pizzio (Viru)
Patricio Sobrero (Pato O)
Sergio Simonetta (Sergio)
Christian Hainich (Hatri)
Julián Cardozo (Juli)
Fernanda Rubio (Fer)
Marcelo Katz (Fito)
Tristan Beckinschtein (Tris)
Alejandro Murad (Ale)
Gabriela Ferreyra (Gabi)
M. Laura Grilli (Laura)
Paola Yanielli (Pao)