English version

Precise timing is ubiquitous and of great importance for physiology and behavior. Indeed, biological timing includes diverse time-related mechanisms that encompass several orders of magnitude, from microsecond processing to seasonal rhythms.
In the Laboratory of Chronobiology we study biological timing, with special emphasis on two temporal scales: circadian timing and time estimation in the seconds-to-minutes range.
Circadian timing refers to the range of the 24-h, and governs a large array of physiological, metabolic and behavioral functions. In mammals, the circadian clock is located in the suprachiasmatic nuclei (SCN) of the hypothalamus. Most – if not all – organisms exhibit daily and circadian rhythms with periods of ca. 24-h, which also serve as the basis for seasonal-encoding mechanisms and might be related to lifespan-related processes. In the seconds-to-minutes range, interval timing is involved in a number of fundamental behaviors such as foraging, decision-making and learning, via activation of cortico-striatal circuits.

Research lines

  • Signaling pathways involved in photic synchronization of the mammalian circadian clock.
  • Interactions between the circadian system and the immune system.
  • Role of glia in the intercellular communication.
  • Analysis of behavioral and metabolic variables through the development of animal models with circadian disorders.
  • Assessment of risk factors and sleep – wake cycle in different populations at risk.
  • Temporal processing in the seconds-to-minutes range: interaction with the circadian system.
  • Daily variations in decision making.
  • Circadian rhythms in Caenorhabditis elegans.

Staff

DIRECTOR
Dr. Diego A. Golombek
Full Professor
National University of Quilmes/CONICET

RESEARCHES

Dr. Juan J. Chiesa
Associate Professor
National University of Quilmes/CONICET

Dr. Patricia V. Agostino
Assistant Professor
National University of Quilmes/CONICET

Dr. Natalia Paladino
Assistant Professor
National University of Quilmes/CONICET

Dr. Santiago A. Plano
Assistant Professor
National University of Quilmes/CONICET

Dr. María Juliana Leone
Assistant Professor
National University of Quilmes/CONICET

POST-DOCS

Dr. M. Laura Migliori
National University of Quilmes

Dr. Rosana Rota
National University of Quilmes

Ph.D. STUDENTS

Lic. Malena Mul Fedele
M.Sc. in Biotechnology

Lic. M. Soledad Alessandro
M.Sc. in Biotechnology

Ms. Eng. Carlos Caldart (Charly)
Engineer in Biophysics
Master in Medical Physics

Lic. Melisa Lambert
M.Sc. in Biotechnology

Lic. Julieta Acosta
M.Sc. in Biotechnology

Lic. Giannina Bellone
Ms. In Psychology

Lic. Ignacio Aiello
M.Sc. in Biotechnology

Lic. Laura Trebucq
M.Sc. in Biotechnology

STUDENTS

Francisco Silva
Biotechnology

CLOSE COLLABORATORS

Dr. Luciano Marpegan
CONICET

Dr. Rodrigo Laje
National University of Quilmes/CONICET

FORMER MEMBERS
Paola Yanielli (Pao)
Gabriela Ferreyra (Gabi)
Alejandro Murad (Ale)
M. Laura Grilli (Lau)
Tristan Beckinschtein (Tris)
Gastón Pizzio (Viru)
Sergio Simonetta
Christian Hainich (Hatri)
Marcelo Katz (Fito)
Fernanda Rubio (Fer)
Julián Cardozo (Juli)
Patricio Sobrero (Pato O)
Micaela do Nascimento (Mica)
Anastasia Herrero (Anas)
Andrés Romanowski (Andrew)
Jonathan Modernel (Jony)
José Duhart (Jose)
Lucila Brocardo (Lu)
Agustín Carpaneto (Agus)
Luciano Brum (Lucho)
Leandro Casiraghi (Lea)
Ivana Bussi (Ivy)
Fernanda Román (Fer2)
Maria Eugenia Goya (Euge)
Fernando M. Baidanoff (Fer)